11 results
Leigh Syndrome 
History: 19-month-old girl with hypotonia, developmental 
delay, failure to thrive, and bilateral optic disc
Leigh Syndrome ... patterns (this case ... #Clinical #MRI ... #Brain #Diagnosis ... #Radiology
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent
Multiple Ring-Enhancing Lesions:
 • Toxoplasmosis (CD4 < 100)
 • Other
Diagnosis- Compatible syndrome ... + MRI lesions + ... RingEnhancing #Lesions #Brain ... differential #diagnosis #causes ... #radiology #neurology
COVID-19 - A Seattle Intensivist's One-Page Cheat-Sheet on COVID-19 v2.7 Updated March 26 2020

(v2.7) incorporating newer
COVID-19 - A Seattle ... 31 • First US case ... dyspnea • 15% URI ... Cheatsheet #Diagnosis #Management ... #Coronavirus #CriticalCare
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
parietal lobes of the brain ... parietal lobes of the brain ... the underlying cause ... until cause identified ... #diagnosis #management
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Epidemiology: • 1-2 cases ... like illnesses, COVID ... axonal form • MRI ... #diagnosis #management
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
muscles: “myasthenic crises ... Myotonic dystrophy - Brain ... Myasthenia Crises ... immunosuppressants - Meds ... Gravis #diagnosis #management
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
anaphylaxis, toxins/meds ... O2 delivery • MI ... Classification #diagnosis #management ... #Overview #criticalcare ... #differential #causes
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
exclude other causes ... ancestry, LGE on MRI ... ARB/ACE-I/ARNI/MRA ... teratogenic GDMT meds ... #cardiology #treatment
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
anaphylaxis, toxins/meds ... O2 delivery • MI ... Classification #diagnosis #management ... #Overview #criticalcare ... #differential #causes
ECMO Troubleshooting - OnePager Summary
ECMO Emergency Protocol - Team should train/practice & have necessary supplies at
circuit and can cause ... EMBOLISM - can cause ... POST-CANNULATION SYNDROME ... #differential #management ... #criticalcare