85 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
suspect underlying hematologic ... disorders • Diagnosis ... #HES #Hematology ... #eosinophils #diagnosis ... #management #algorithm
Connective tissue disease-associated interstitial lung diseases

LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
SSc: systemic sclerosis ... PSS: Sjogren syndrome ... LungDisease #CTILD #Diagnosis ... Differential #Comparison #Table ... #Pulmonary #Rheumatology
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
guidelines General - Systemic ... splenomegaly, abnormal neurology ... cell disease Rheumatology ... Pathway #Child #Peds ... #Pediatrics #Diagnosis
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... • Scleroderma (Systemic ... Autoantibodies #Rheumatology ... #diagnosis #associations ... #table
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome ... Neuro disease: • Systemic ... Behcets #disease #Syndrome ... #Treatment #management ... #pharmacology #rheumatology
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
• Homogeneous: Systemic ... ) • Speckled: Systemic ... SLE), Sjogren's Syndrome ... ANA #patterns #rheumatology ... #diagnosis #differential
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... Periodic fever syndromes ... hypersensitivity syndromes ... #Diagnosis #Management ... #Hematology #Rheumatology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
block • Sjogren syndrome ... polymyositis overlap syndrome ... #SLE #Summary #diagnosis ... #rheumatology # ... management
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... Demyelinating Syndrome ... Erythematosus #SLE #CNS #neurology ... #rheumatology # ... #management #treatment
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
- Differential Diagnosis ... Neurologic-Centered ... capillary leak syndrome ... • Schnitzler syndrome ... #hematology #oncology