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diagnosis management hematology oncology differential syndrome dermatomyositis hodgkins vasculitis antimda5 antimda5dm antinxp2 antinxp2dm behcet comparison cryofibrinogenemia cryoglobulinemia cryoglobulins dermatologic disease
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Autoimmune diseases • Clinical ... translocation • Types: Classification ... Noncontiguous spread • Clinical ... disease: GI, neuro, cutaneous ... #differential #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
- Clinical Presentation ... (90-95% of cases ... ) Classification ... #diagnosis #classification ... #hematology #oncology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... • Non-Hodgkin lymphoma ... • Angiocentric lymphoma ... rash #diagnosis #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... vasculitis) • Cutaneous ... Behcet syndrome (Clinical ... Ischemia, Leukemia, Lymphoma ... signs #symptoms #rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Marginal Zone Lymphoma ... Alpha & Mu) Skin ... gangrenosum • Cutaneous ... Marginal zone lymphoma ... Paraproteinemias #Hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
gland) biopsy • Ocular ... Hypocomplementemia • Can cause ... salivary ducts Clinical ... ) • Cutaneous vasculitis ... Sjogrens #Syndrome #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... aphthous ulcers, cutaneous ... strong sign of cutaneous ... differential #diagnosis #rheumatology ... #classification
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
DERMATOMYOSITIS Cutaneous ... ulcerations • Skin ... auricular papules Clinical ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... 3rd Decade Skin ... Disease Classification ... Erythematous, macular ... Non-autoimmune rheumatologic
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... violaceous, nontender cutaneous ... and secondary lymphoid ... CLL -> Invade Skin ... #Leukemia #Hematology
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