9 results
Algorithm for Differentiating Gitelman syndrome from Bartter syndrome
 • Urine Chloride
 • Urine Ca/Cr ratio

Dr. Krithika
Differentiating Gitelman ... Chloride • Urine ... krithicism #Gitelman ... #Algorithm #nephrology ... #hypokalemia #diagnosis
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... , mild hypomagnesemia ... potassium wasting) • Hypomagnesemia ... • Congenital chloride ... #nephrology #management
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... thiazide-sensitive sodium-chloride ... H+ secretion → Hypokalemia ... Hypermagnesuria, Hypomagnesemia ... #nephrology #diagnosis
Hypomagnesemia - Differential Diagnosis
Renal Causes of Hypomagnesemia - Familial:
Bartter syndrome and Gitelman syndrome, Isolated recessive hypomagnesemia,
Hypomagnesemia - ... Familial: Bartter syndrome ... and Gitelman syndrome ... with secondary, hypocalcemia ... diagnosis #causes #nephrology
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
Hypomagnesemia - ... Hypercalcemia - Hypokalemia ... - Gitelman ... syndrome - ... Classification #Causes #Workup
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Causes of Hypokalemia ... Renal K loss • Hypomagnesemia-induced ... hypokalemia • ... , Gitelman's syndrome ... algorithm #causes #nephrology
Gitelman Syndrome - Diagnosis and Workup
Blood Work:
 - Hypokalemia
 - Hypomagnesemia
 - Metabolic Alkalosis
 - Elevated
Gitelman Syndrome ... Hypokalemia - Hypomagnesemia ... dr_missyhanna #Gitelman ... #Syndrome #Diagnosis ... #Workup #nephrology
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Alcoholism (worsened by hypomagnesemia ... diuretic use), Gitelman's ... syndrome (mimics ... Fever Other: - Hypomagnesemia ... differential #diagnosis #nephrology
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Alkalosis - Urinary Chloride ... diuretic use, Bartter syndrome ... , Gitelman syndrome ... , Hypomagnesemia ... urine #Algorithm #nephrology