11 results
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... ) Pathophysiology ... free fatty acid metabolism ... iMedEducation #AFLP ... Liver #Pregnancy #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Cholestasis • ALP ... disease • If ALP ... • Elevation of ALP ... AST:ALT Ratios ... #differential #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Shock liver • Metabolic ... disease - If ALP ... be abnormal AST ... hemolysis) • ALP ... diagnosis #algorithm #hepatology
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
and Bilirubin Metabolism ... insult Bilirubin metabolism ... #ASTALT #AlkPhos ... #Bilirubin #Hepatology ... #Pathophysiology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
in 1923 Low ALP ... 1948 by Rathbun ALP ... collection with EDTA Pathophysiology ... Nephrolithiasis • Metabolic ... Hyophosphatasia #hepatology
Refeeding Syndrome: Pathogenesis and clinical findings

Patients at Risk of Refeeding Syndrome:
 - Little or no nutritional
glucose, fluid, salt ... • Incr Glucose Metabolism ... Syndrome - Metabolic ... PO4 -> decr RBC ATP ... Syndrome #diagnosis #pathophysiology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... Nucleotidase • ALT ... obstruction • ALP ... diagnosis #workup #hepatology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
box indicates all ... The presence of metabolic ... ALP, alkaline phosphatase ... ; ALT, alanine aminotransferase ... Abnormal #Algorithm #Hepatology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
♀, ↑Age, ESRD Pathophysiology ... Management: • D/c all ... necrosis) • Start ... Management #Treatment #Hematology
Rickets and Osteomalacia: Pathogenesis and Clinical Findings
 • Calcification inhibitors (excess exposure to A1, Fluoride, etidronate)
enzymes (like ALP ... Abnormal Vitamin D Metabolism ... #Osteomalacia #pathophysiology