8 results
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Fatty Liver of Pregnancy ... (AFLP) Pathophysiology ... free fatty acid metabolism ... iMedEducation #AFLP ... #hepatology #obstetrics
Pathophysiology of Hemolytic Anemia
 - Defects in RBC internal contents (thalassemia, hemoglobinopathies, and metabolic defects)
 -
Pathophysiology ... of Hemolytic Anemia ... hemoglobinopathies, and metabolic ... environment #Pathophysiology ... #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Pregnancy) - Low ... Disease • Parasites ... #Macrocytic #Anemia ... Algorithm #Causes #Hematology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
in 1923 Low ALP ... • Pernicious anemia ... collection with EDTA Pathophysiology ... Nephrolithiasis • Metabolic ... Hyophosphatasia #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Shock liver • Metabolic ... melanoma, myeloma • Pregnancy ... • AST/ALT > ALP ... disease - If ALP ... diagnosis #algorithm #hepatology
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Bandemia Overview ... ingestions • Metabolic ... Degree of bandemia ... neutrophil #WBC #CBC #hematology ... #pathophysiology
Etiologies of Folate Deficiency
 • Decreased dietary intake - uncommon in this era
 • Increased requirements
Patients who are pregnant ... have hemolytic anemia ... aspects of folate metabolism ... addition, folate metabolism ... differential #diagnosis #hematology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... obstruction • ALP ... cholestasis of pregnancy ... diagnosis #workup #hepatology