19 results
Thyroid Goiter on Physical Exam

Mother and daughter both presenting with thyroid goiters caused by iodine deficiency.
caused by iodine deficiency ... PhysicalExam #iodine #deficiency ... #endocrinology ... #clinical #video ... #neck #hypothyroidism
C5-C9 Deficiency - Pathogenesis and Clinical Findings
Note:
 • Risk of invasive meningococcal disease is 1000-10000x higher
C5-C9 Deficiency ... Pathogenesis and Clinical ... infections • Clinical ... -> Headache, neck ... C5C9Deficiency #Complement #pathophysiology
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings
The epidemiology of this disease is 1/340,000 births and roughly double
Pathogenesis and clinical ... involved in B cell maturation ... BTK -> Impaired maturation ... antibodies) -> Complete deficiency ... Agammaglobulinemia #XLinked #pathophysiology
Ketosis Disorders
Ketone bodies are a normal metabolic energy source. Excessive unregulated production of ketones, often accompanied
complete insulin deficiency ... partial insulin deficiency ... Nick Mark MD @nickmmark ... Disorders #ketones #differential ... diagnosis #management #endocrinology
Hypothyroid Myopathy
Very common (up to 80% ) in patients with hypothyroidism
Pathophysiology:
 • T4 deficiency leads to
hypothyroidism Pathophysiology ... : • T4 deficiency ... fibers Spectrum of Clinical ... Hypothyroid #Myopathy #pathophysiology ... signs #symptoms #endocrinology
Hypoxia and Hypoxemia - Overview
Hypoxia - insufficient oxygen delivered to tissues to meet demands
Hypoxemia - low
SaO2 - percent saturation ... Nick Mark MD @nickmmark ... summary #pulmonary #differential ... diagnosis #causes #pathophysiology
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
21-Hydroxylase Deficiency ... Pathogenesis and Clinical ... amount of enzyme deficiency ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... #genetics #endocrinology
Pulse Oximetry Summary
Pulse oximetry is the non-invasive continuous measurement of the oxygen saturation of hemoglobin. It
of the oxygen saturation ... deoxy hemoglobin differentially ... signal strength Nick ... #critcalcare #pathophysiology
Thiamine Deficiency - Differential Diagnosis Framework and Clinical Manifestations

Causes of Thiamine Deficiency:
 • Poor intake:
	- Diets
Thiamine Deficiency ... - Differential ... Framework and Clinical ... Manifestations #Differential ... beriberi #nutrition #pathophysiology
Hypoglycemia - Differential Diagnosis Algorithm
Fasting Hypoglycemia:
 • Excess Insulin
 • Medications (e.g. Insulin Secretagogues, ß-Adrenergic Antagonists,
Hypoglycemia - Differential ... Other Causes: • Critical ... Catecholamine Deficiency ... Hypoglycemia #LowGlucose #Differential ... Diagnosis #Algorithm #endocrinology