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msk pain approach antibodies antinuclear autoimmune biliary cholangitis classification dermatologic dermatology erythematosus fungal gap globulin gpa granulomatosis hepatology infections infectiousdiseases
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Pain - Diagnostic ... #rheumatology # ... approach #workup ... #differential # ... diagnosis #arthritis
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
: The ANA patterns ... Patterns and Associated ... Primary Biliary Cirrhosis ... #patterns #rheumatology ... #diagnosis #differential
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary Cirrhosis ... Pathophysiology ... bile ducts Differential ... #diagnosis #workup ... #hepatology
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
Disease: • Pain ... #Pain #MSK #rheumatology ... #approach #workup ... #differential # ... diagnosis #arthritis
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Differential Diagnosis ... • Is there a pattern ... Joint #pain #Differential ... #Diagnosis #MSK ... #rheumatology #
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... iron saturation ... #laboratory #workup ... #diagnosis #testing ... #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Diagnosis: • ANCA-associated ... : • Joint pain ... arthropathy • 90% joints ... #Rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
surfaces of the joints ... reticularis Differential ... • Giant cell arteritis ... with a certain pattern ... #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential ... vesicular eruption - Joints ... ) pattern: antibodies ... ) pattern: is usually ... #diagnosis #rheumatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... (RA, Temporal arteritis ... : Cirrhosis, ETOH ... gastric tumors • Hematology ... #diagnosis #hematology
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