7 results
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Polyangiitis (GPA ... GPA causes disease ... Diagnosis: Vasculitis ... #dermatology #rash ... #diagnosis #rheumatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Joint Pain Rash ... Sarcoidosis • GPA ... Sarcoidosis #dermatology ... #skin #rashes #differential ... #diagnosis #rheumatology
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
- GPA Cutaneous ... : • Behcet Disease ... #skin #dermatology ... #rheumatology # ... differential #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
> PR3 60% • GPA ... mucositis - Rash ... • ANCA (Dx: GPA ... differential #diagnosis ... #rheumatology #
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... (RA, Temporal arteritis ... : Cirrhosis, ETOH ... gastric tumors • Hematology ... #diagnosis #hematology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Differential Diagnosis ... MPO > PR3 60/ GPA ... #Differential #Diagnosis ... #Rheumatology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Heavy Chain disease ... Pseudohyponatremia • ↓anion gap ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology