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diagnosis hematology differential oncology algorithm hairloss anemia aplastic cryofibrinogenemia diffuse focal generalized hair leukemia loss management mds myelodysplasia myelodysplastic nonpalpable
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm DIFFUSE Scarring - Irreversible-biopsy required • Lupus
• Loose anagen syndrome ... decalvans - Secondary ... to Skin Disease ... #dermatology #Differential ... Diagnosis #Algorithm #causes
Allopecia - Differential Diagnosis Framework for Hair Loss Localized / Focal Hair Loss Pattern: • Scarring Alopecia:
Capitis - Skin ... , Loose anagen syndrome ... Examine the entire skin ... disorder • Atopic ... Differential #Diagnosis #dermatology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Systemic and Primary Causes ... ) • Atopic dermatitis ... Myelodisplastic syndrome ... Pruritus #primary #secondary ... #generalized #dermatology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... leakage of RBC's secondary ... Kasabach-Merritt syndrome ... Differential #Diagnosis #hematology ... #rheumatology #
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
cryoglobulins • Negative causes ... Antiphospholipid syndrome ... Warfarin-induced skin ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Damage to Marrow (Toxic ... Constitutional Syndromes ... Headaches • Pale skin ... and petechiae Causes ... Anemia #oncology #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... just beneath the skin ... that are caused ... DDX: Rule Out Secondary ... #diagnosis #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... • Tumor lysis syndrome ... bone marrow and secondary ... CLL -> Invade Skin ... #Leukemia #Hematology
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