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diagnosis hematology differential algorithm rash vasculitis anemia aplastic classification cryofibrinogenemia cryoglobulinemia cryoglobulins cutaneous dermatologic generalized gpa granulomatosis leukemia management mds
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... CAUSES OF PALPABLE ... Differential #Diagnosis #hematology ... #rheumatology # ... #dermatology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Systemic and Primary Causes ... ) • Atopic dermatitis ... Myelodisplastic syndrome ... Pruritus #primary #secondary ... #generalized #dermatology
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
Involving the Skin ... Leukocytoclastic Vasculitis Secondary ... Vessel: Petechiae, Palpable ... Disease • Cogan syndrome ... #dermatology #rheumatology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... in primary or secondary ... cryoglobulins • Skin ... Diagnosis #Algorithm #Causes ... #dermatology #physicalexam
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... • Petechiae, Palpable ... • Petechiae • Palpable ... • Goodpasture syndrome ... rash #diagnosis #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... - Purpura - Skin ... Clinical triad of Palpable ... Type III Often Secondary ... classification #rheumatology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
cryoglobulins • Negative causes ... Antiphospholipid syndrome ... Warfarin-induced skin ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Damage to Marrow (Toxic ... Headaches • Pale skin ... and petechiae Causes ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... just beneath the skin ... DDX: Rule Out Secondary ... #diagnosis #hematology ... #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
• Tumor lysis syndrome ... bone marrow and secondary ... CLL -> Invade Skin ... #Leukemia #Hematology ... #Oncology #Diagnosis
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