11 results
Renal Tubular Acidosis - Diagnosis Algorithm
 • Hyperkalemic Type 4 RTA
 • Hypokalemic Type 1 RTA
Renal Tubular Acidosis ... - Diagnosis Algorithm ... Type 4 RTA • Hypokalemic ... #Acidosis #Diagnosis ... #Algorithm #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
thiazide-sensitive sodium ... thiazide-sensitive sodium ... distal convoluted tubule ... acidosis (RTA)) ... Syndrome #diagnosis #nephrology
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Diagnosis Algorithm ... • Metabolic acidosis ... Bartter syndrome, Gitelman ... potassium #low #nephrology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Differential Diagnosis Algorithm ... • Renal tubular ... acidosis (type ... Bartter's syndrome, Gitelman's ... #causes #nephrology
Renal Tubular Acidosis - Differential Diagnosis Algorithm
Decreased Serum K, Urine pH < 5.5 - Proximal RTA
Decreased
Renal Tubular Acidosis ... Differential Diagnosis Algorithm ... Urine pH > 6.0 - Hypokalemic ... #Diagnosis #Algorithm ... #nephrology
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
ascending limb Gitelman ... cell epithelial sodium ... of epithelial sodium ... acidosis - alpha-Intercalated ... Defects #Kidney #Nephrology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... thiazide-sensitive sodium-chloride ... in the distal tubule ... H+ secretion → Hypokalemia ... Pathophysiology #nephrology
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Urinary Chloride Algorithm ... Bartter syndrome, Gitelman ... settings, the urine sodium ... the excretion of sodium ... #nephrology #differential
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
Algorithm Before ... Bartter syndrome, Gitelman ... - Metabolic acidosis ... #diagnosis #Algorithm ... differential #potassium #nephrology
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... tobacco, Renal tubular ... acidosis, Postobstructive ... diuretic use), Gitelman's ... differential #diagnosis #nephrology