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rheumatology management differential joint pain workup approach leukemia lupus signs syndrome treatment vasculitis atopic atopy behcet causes classification cll comparison
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Differential Diagnosis ... constitutional symptoms ... • SLE • Psoriatic ... #Differential #Diagnosis ... #MSK #rheumatology
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
or nerve root Symptoms ... : • Acute or chronic ... e.g., meniscal tears ... #Joint #Pain #MSK ... #differential #diagnosis
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Oral aphthae : SLE ... Giant retinal tears ... : SLE, Reactive ... Recurrent and chronic ... #rheumatology #
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... , Arthritis, myalgia ... constitutional symptoms ... • Evolution: Chronic ... #diagnosis #management
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... at the time of diagnosis ... Extrapulmonary: ankle arthritis ... anterior/posterior MSK ... #Sarcoidosis #Diagnosis
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
to Joint Pain - Diagnostic ... rheumatic fever • Chronic ... = RA, SLE, psoriatic ... #Joint #Pain #MSK ... #rheumatology #
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... Chronic leukemia ... onset of symptoms ... #Leukemia #Hematology ... #Oncology #Diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... vein thrombosis Hematologic ... Induced Lupus: • Symptoms ... with Lupus: • Chronic ... Erythematosus #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... non-Hodgkin lymphoma SLL ... with no early symptoms ... #workup #oncology ... #hematology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... Presentation: Systemic Symptoms ... • Progressive symptoms ... Eosinophilia, asthma, chronic ... #Rheumatology
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