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differential management arthritis leukemia pain vasculitis workup approach autoimmune classification cll disease erythematosus gout lupus lymphocytic mds monoarthritis monoarticular myelodysplasia
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
meningitis), MCC CNS symptoms ... Giant retinal tears ... Recurrent and chronic ... #Syndrome #diagnosis ... #rheumatology #
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
or nerve root Symptoms ... : • Acute or chronic ... e.g., meniscal tears ... #Pain #MSK #rheumatology ... #differential #diagnosis
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Arthritis Differential Diagnosis ... constitutional symptoms ... - Autoimmune Rheumatologic ... #Differential #Diagnosis ... #MSK #rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
bone pain, fever, joint ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... with no early symptoms ... • Richter’s Syndrome ... #workup #oncology ... #hematology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
• Progressive symptoms ... Eosinophilia, asthma, chronic ... Palpable purpura, joint ... vasculitis • Behcet ... #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Arthritis: • Joint ... Induced Lupus: • Symptoms ... with Lupus: • Chronic ... #Rheumatology
Gout - Diagnosis and Management Summary 3 Conditions for Gout to Manifest: 1. Hyperuricemia 2. Monosodium urate deposition in
deposition in joints ... sex • Metabolic syndrome ... attacks • Other joints ... 2 attacks in a year ... management #treatment #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Eosinophilia, asthma, chronic ... vesicular eruption - Joints ... VASCULITIS: • Behçet ... Presentation - Systemic Symptoms ... #rheumatology #
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes ... age 70 years Symptoms ... Marrow Failure • Chronic ... #diagnosis #hematology ... #oncology
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