39 results
Hypercortisolism (Cushing syndrome) - Simplified Differential Diagnosis Algorithm
Exogenous (ACTH-independent)
Endogenous
 • ACTH-dependent:
    - ACTH-secreting
Differential Diagnosis Algorithm ... : - Adrenal ... hyperplasia - Adrenal ... Differential #Diagnosis #Algorithm ... #endocrinology
Adrenal Insufficiency Differential Diagnosis Algorithm
Clinical suspicion: Weakness, fatigue, nausea, musculoskeletal pain, dizziness, volume depletion, abdominal pain,
Differential Diagnosis Algorithm ... Baseline plasma ACTH ... High baseline ACTH ... Differential #Diagnosis #Algorithm ... #endocrinology
Adrenal Insufficiency - Differential Diagnosis Workup Algorithm
Primary Adrenal Insufficiency:
 • Autoimmune primary adrenal insufficiency
 • Adrenoleukodystrophy,
Diagnosis Workup Algorithm ... Primary Adrenal ... apoplexy • Isolated ACTH-deficiency ... Diagnosis #Workup #Algorithm ... #endocrinology
Diagnosis Adrenal Insufficiency - Algorithm

Step 1) Screening Test: 6-8AM Cortisol Level
 - Early morning cortisol levels
Diagnosis Adrenal ... Insufficiency - Algorithm ... gland) #Adrenal ... Insufficiency #Algorithm ... #Stimulation #Endocrinology
Causes of Adrenal Insufficiency - Differential Diagnosis Algorithm
ACTH-Dependent (Secondary):
 • Pituitary Dysfunction
 • Hypothalamic Dysfunction
ACTH-Independent (Primary):
Differential Diagnosis Algorithm ... ACTH-Dependent ... Hypothalamic Dysfunction ACTH-Independent ... Differential #Diagnosis #Algorithm ... #Causes #endocrinology
Adrenal Insufficiency Diagnosis Algorithm - Evaluation of HPA Axis Response to ACTH

Early am cortisol < 3
Adrenal Insufficiency ... Diagnosis Algorithm ... Axis Response to ACTH ... Insufficiency #Diagnosis #Algorithm ... #Test #Endocrinology
Benign Adrenal Mass - Differential Diagnosis Algorithm
Hyperplasia - Often Bilateral
 • Congenital Adrenal Hyperplasia
 • ACTH
Benign Adrenal Mass ... • Congenital Adrenal ... Hyperplasia • ACTH ... Dependent • ACTH ... #Endocrinology
Adrenal Insufficiency Diagnosis Algorithm
Test 1: Baseline AM Cortisol 
 - Beware of major normal value
 -
Adrenal Insufficiency ... Diagnosis Algorithm ... pregnancy) Test 2: ACTH ... BCM_InternalMed #Adrenal ... #endocrinology
Adrenal Insufficiency Diagnosis Algorithm
Clinical features: 
 - Weight loss, anorexia, Weakness, fatigue, GI distress
 - Hypotension,
Diagnosis Algorithm ... skin (due to high ACTH ... findings (see algorithm ... Insufficiency #Diagnosis #Algorithm ... Stimulation #StimTest #Endocrinology
Primary vs Secondary Adrenal Insufficiency - Pathophysiology
Primary AI = adrenal glands themselves are the problem. This
Primary vs Secondary Adrenal ... be low, while ACTH ... Low ACTH leads to ... limited adrenal ... Pathophysiology #endocrinology