29 results
Ophthalmoplegia secondary to Orbital Apex Syndrome

A 61-year-old man presented with retro-orbital pain, near-complete ophthalmoplegia, loss of
to Orbital Apex Syndrome ... A 61-year-old ... Orbital #Apex #Syndrome ... #Clinical #Video ... #PhysicalExam #NEJM
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
Clinical Syndrome ... : • Common Clinical ... Features: alveolitis, ear ... myeloid cells NEJM ... Autoinflammatory #Somatic #rheumatology
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Hypereosinophilic Syndrome ... Hypereosinophilic Syndrome ... • Clinically ... #HES #Hematology ... eosinophils #diagnosis #management
Susac Syndrome - Clinical Triad
 - Central nervous system dysfunction
 - Branch retinal artery occlusion
 -
Susac Syndrome - ... Clinical Triad ... disease flares - 2-year ... Triad #Diagnosis #Management ... #Rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... (Clinical Dx). ... Giant retinal tears ... #diagnosis #management ... signs #symptoms #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... Clinical Presentation ... Fever is the main clinical ... #Diagnosis #Management ... #Hematology #Rheumatology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... renal failure Clinical ... Specific sarcoidosis syndromes ... • Heerfordt syndrome ... Sarcoidosis #Diagnosis #Management
Marfan’s Syndrome with Ectopia Lentis - Slit-lamp examination revealed ectopia lentis in both eyes, including near-complete
Marfan’s Syndrome ... eyes, including near-complete ... #Clinical #Ophth ... LensDislocation #SlitLamp #NEJM
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... cases/100,000 per year ... meningococcal, H1N1) Clinical ... Guillain-Barre Clinical ... #diagnosis #management
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
of 37°C to the near-freezing ... Cryofibrinogenemia Clinical ... Diagnosis: • + Clinical ... Antiphospholipid syndrome ... Cryofibrinogenemia #diagnosis #rheumatology