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diagnosis causes common disorders erythematosus hemophagocytic hypogammaglobulinemia immunodeficiency immunology lupus lymphohistiocytosis macrophage platelet sle systemic thrombocytopenia treatment variable workup
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Syndrome (MAS) ... with leukopenia, anemia ... thrombocytopenia • Liver ... #Management #Hematology ... #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... age, however the disease ... acute or subacute ... lymph node, or liver ... #treatment #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
family history - Medications ... IgA, IgG, IgM (CVID ... changes), high MCV anemia ... disease), HBsAg ... Causes #Workup #hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Liver diseases ... autoimmune hemolytic anemia ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... hypogammaglobulinemia #immunology #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... lymphopenia, low PLT • Anemia ... Chronic B-cell activation ... and/or medications ... Erythematosus #Diagnosis #Rheumatology
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