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diagnosis hematology chronic cll lymphocytic oncology cvid differential gap globulin hemeonc hypogammaglobulinemia immunodeficiency immunology protein proteingap variable workup
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Epidemiology: • Most common ... • Neutropenia, anemia ... • Richter’s Syndrome ... • GI complications ... • Sezary syndrome
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Overview: • Most common ... routine CBC (rnost common ... 5) Symptoms of anemia ... thrombocytopenia Complications ... hemeonc #diagnosis #management
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
noninfectious complications ... autoimmune hemolytic anemia ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... #diagnosis #management
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
changes (POEMS syndrome ... Liver disease: Cirrhosis ... : Lymphoma, Leukemia ... Thalassemia, Sickle cell anemia ... Comment on type
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