18 results
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Clotmaster #VTE #DOAC ... Edoxaban #Loading #DVT ... #Pharmacology # ... Hematology
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
stratification algorithm ... for the treatment ... DVT = deep vein ... #Cancer #Algorithm ... Anticoagulation #Management #Hematology
Treatment Algorithm for First Time DVT
 • Provoked
 • Unprovoked
 • Active Malignancy

By Carlin Rooke, MD.

#DVT
Treatment Algorithm ... for First Time DVT ... #DVT #Treatment ... #Algorithm #management ... #hematology #VTE
Venous Thromboembolism Treatment Algorithm
Branch points: 
Active bleeding?  Active malignancy? Provoked?

- Dr. Joseph Shatzel
@Clotmaster

#Management #VTE #DVT
Thromboembolism Treatment ... Algorithm Branch ... Management #VTE #DVT ... #Algorithm #Venous ... #Hematology #Anticoagulation
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
suspect underlying hematologic ... Diagnosis and Treatment ... Algorithm Matthew ... #HES #Hematology ... diagnosis #management #algorithm
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
Treatment algorithm ... and incidental DVT ... without concomitant DVT ... DOAC, direct oral ... Anticoagulation #Management #Hematology
Recurrent / Breakthrough DVT During Anticoagulation

Subtherapeutic Anticoagulation
Hypercoagulable State 
 - Antithrombin deficiency 
 - Hypercoagulability ot
/ Breakthrough DVT ... - May-Thurner syndrome ... Breakthrough #Recurrent #DVT ... anticoagulation #hematology ... #differential #algorithm
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
(DOAC interactions ... ) Cancer-treatment ... DOACs are substrates ... Chemotherapy #Oncology #Hematology ... Interactions #Table #Pharmacology
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
DOAC Reversal Emergency ... anticoagulant treatment ... not available #DOAC ... anticoagulant #hematology ... #management #pharmacology
Causes of Pleural Effusion - Differential Diagnosis Algorithm
Transudate - Hydrostatic
 • Congestive heart failure
 • Constrictive
Differential Diagnosis Algorithm ... • Uremia • Meigs ... nail syndrome ... Pulmonary #Diagnosis #Algorithm ... #Hepatology #causes