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anticoagulation management oncology vte anticoagulant cancer malignancy oral bridging chemotherapy cyp3a4 dabigatran dosing edoxaban inducers inhibitors interactions loading noac pglycoprotein
Oral anticoagulant dosing and bridging for VTE - Dr. Joseph Shatzel @Clotmaster #VTE #DOAC #Bridging #Dosing #Oral
Clotmaster #VTE #DOAC ... Anticoagulation #Dabigatran #Apixaban ... Edoxaban #Loading #DVT ... #Pharmacology # ... Hematology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓) of cytochrome p450 CYP3A4 and P-glycoprotein. DOACs are substrates
) Cancer-treatment ... rivaroxaban, and apixaban ... Rivaroxaban and apixaban ... Chemotherapy #Oncology #Hematology ... Interactions #Table #Pharmacology
DOAC Reversal Emergency surgery or urgent procedure Stop anticoagulant treatment; volume resuscitation and transfusion as needed Antidotes: • Apixaban,
anticoagulant treatment ... Antidotes: • Apixaban ... not available #DOAC ... anticoagulant #hematology ... #management #pharmacology
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis. Currently, edoxaban and rivaroxaban are the only
stratification algorithm ... for the treatment ... DVT = deep vein ... #Cancer #Algorithm ... Anticoagulation #Management #Hematology
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 Treatment algorithm for VTE in Malignancy (A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
Treatment algorithm ... and incidental DVT ... without concomitant DVT ... DOAC, direct oral ... Anticoagulation #Management #Hematology
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