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diagnosis differential classification vasculitis approach cryoglobulinemia cryoglobulins erythematosus joint lupus msk myopathy myositis pain sle systemic types vasculitides workup
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
present both at rest ... trauma (e.g., meniscal ... e.g., congenital hip ... osteopetrosis, avascular ... Joint #Pain #MSK #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Vascular Sludging ... HBV infection, HIV ... infection • Autoimmune ... arthralgia, and arthritis ... classification #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
disease • Non-autoimmune ... rheumatologic diseases ... deficiencies • Autoimmune ... • Malar rash - spares ... Erythematosus #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
and bullous or vesicular ... • Cogan Syndrome ... retinopathy Lab Tests ... Cryoglobulins • HIV ... differential #diagnosis #rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Diagnostic Tests ... RP-ILD), dermato-rheumatologic ... weakness + atrophy- Hip ... • Nonerosive arthritis ... muscle disease/muscular
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