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differential rheumatology msk vasculitis workup approach autoimmune causes cryoglobulinemia cryoglobulins dementia effusions erythematosus geriatrics joint knee lupus mncd myopathy myositis
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
present both at rest ... trauma (e.g., meniscal ... e.g., congenital hip ... osteopetrosis, avascular ... #differential #diagnosis
Causes of Knee Effusions - Differential Diagnosis Framework Knee Effusion Red Flags: 1. Fever/Chills/Joint pain/Night sweats/Weight loss - DDX: -
- Differential Diagnosis ... Seronegative Reactive Syndrome ... Ligamentous injuries - Meniscal ... #differential #diagnosis ... #msk #physicalexam
Major neurocognitive disorders (MNCD): Diagnosis and workup 1) Clinical diagnosis Cognitive impairment + loss of autonomy 2)
hydrocephalus, HIV ... ... laboratory tests ... Aphaso-apraxo-agnosia syndrome ... Frontal atrophy Vascular ... Differential #Subtypes #Classification
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Vascular Sludging ... HBV infection, HIV ... arthralgia, and arthritis ... Labs/Diagnosis: ... #types #classification
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... and bullous or vesicular ... retinopathy Lab Tests ... Cryoglobulins • HIV ... #rheumatology #classification
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
, inflammatory arthritis ... Skin Disease Classification ... Differential Diagnosis ... • Malar rash - spares ... Erythematosus #Diagnosis
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential Diagnosis ... Tests: • Measure ... weakness + atrophy- Hip ... • Nonerosive arthritis ... muscle disease/muscular
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