10 results
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Acidosis (MALA) Pathophysiology ... and acute kidney injury ... Clinical presentation also ... LacticAcidosis #Toxicity ... Toxicology #Diagnosis #Management
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
cytotoxic lung injury ... starting amiodarone treatment ... been reported as ... macrophages Treatment ... Pulmonary #diagnosis #management
In ARDS, we know that the lungs are so diffusely injured that the remaining total area
Despite this, it is also ... #pathophysiology ... #diagnosis #management ... #ards #foamed # ... criticalcare #treatment
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
Induced Muscle Toxicity ... myopathies such as ... Direct muscle injury ... Risk of muscle injury ... myopathy #diagnosis #management
Vasospastic (Prinzmetal) Angina
Definition / Epidemiology:
 • Rest angina attributed to coronary artery vasospasm.
 • Patients often
younger than other ACS ... Pathophysiology: ... microvascular injury ... tests in cath lab Treatment ... cardiology #diagnosis #management
Mild-to-Moderate Ulcerative Colitis - Management Algorithm
Curcumin:
 • Natural phytochemical from turmeric
 • 2g/day divided in 2-3
Ulcerative Colitis - Management ... Potential GI SE, liver injury ... • Budesonide Foam ... risk for steroid AEs ... Moderate #Algorithm #treatment
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Lateral Sclerosis (ALS ... lateral sclerosis Pathophysiology ... in improperly folded ... diagnosis column Treatment ... neurology #diagnosis #management
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
Diagnosis and Management ... malignancy Pathophysiology ... levels not useful as ... #Endocrinology ... #Treatment #Pathophysiology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Etiology: • Pathophysiology ... edema visualized as ... Medication/Drug toxicity ... epilepticus Treatment ... Syndrome #diagnosis #management
Management of Anthracyclines and HER2 Antagonist Cardiotoxicity
Anthracyclines cause cardiomyopathy:
 ✖ Reduction in left ventricular ejection fraction
Management of Anthracyclines ... ) and initiate treatment ... plus diuretic as ... detection of cardiac injury ... #pharmacology #toxicity