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diagnosis oncology aflp anemia anthracycline aplastic battery bullous button cardiology cardiotoxicity chemotherapy childhood crisis dermatology differential fatty hepatology her2 immunization
Childhood Immunization Schedule: Why we immunize • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
metabolites induce injury ... hemorrhagic rash; symptoms ... CNS and hematologic ... Immunization #peds #pediatrics ... #pathophysiology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... postpartum): • Initial symptoms ... = nonspecific (nausea ... Liver #Pregnancy #hepatology ... #pathophysiology
Bullous Pemphigoid - Diagnosis and Management Summary Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Diagnosis and Management ... Summary Pathophysiology ... Clinical Signs/Symptoms ... - Erosions and crusts ... #dermatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... Lysis Syndrome: • Pathophysiology ... TLS #diagnosis #management ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Marrow (Toxic injury ... and petechiae Causes ... • Improve the symptoms ... Anemia #oncology #hematology ... #diagnosis #management
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Presentation: Injury ... Bilateral signs and/or symptoms ... • Infectious causes ... Myelitis #diagnosis #management
Pediatric Button Battery Ingestion Most serious BB ingestions are not witnessed. Therefore, have a low threshold for
Pediatric Button ... children with symptoms ... Button batteries cause ... Severity of tissue injury ... toxicology #diagnosis #management
Scleroderma Renal Crisis (SRC) Clinical Presentation of Scleroderma Renal Crisis: 1) Acute kidney injury 2) Abrupt onset of hypertension 3)
) Acute kidney injury ... anemia (MAHA) Pathophysiology ... endothelial cell injury ... of arteries Management ... • Refractory cases
Management of Anthracyclines and HER2 Antagonist Cardiotoxicity Anthracyclines cause cardiomyopathy: ✖ Reduction in left ventricular ejection fraction
Management of Anthracyclines ... Anthracyclines cause ... heart failure symptoms ... detection of cardiac injury ... cardiology #oncology #pharmacology
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