13 results
Adrenal Insufficiency Differential Diagnosis Algorithm
Clinical suspicion: Weakness, fatigue, nausea, musculoskeletal pain, dizziness, volume depletion, abdominal pain,
Differential Diagnosis Algorithm ... Weakness, fatigue, nausea ... , hypoglycemia Testing ... ) stimulation test ... #endocrinology
Adrenal Insufficiency Diagnosis Algorithm - Evaluation of HPA Axis Response to ACTH

Early am cortisol < 3
Adrenal Insufficiency ... Diagnosis Algorithm ... unclear (often the case ... then go to stim testing ... #Test #Endocrinology
Primary Adrenal Insufficiency:
 • ACTH stimulation test - Synthetic ACTH does not stimulate cortisol secretion because
Primary Adrenal Insufficiency ... aldosterone - Low in cases ... adrenal insufficiency ... laboratory #diagnosis #testing ... #endocrinology
Diagnosis Adrenal Insufficiency - Algorithm

Step 1) Screening Test: 6-8AM Cortisol Level
 - Early morning cortisol levels
Diagnosis Adrenal Insufficiency ... - Algorithm ... require Cosyntropin testing ... #Algorithm #Diagnosis ... #Endocrinology
Causes of Adrenal Insufficiency - Differential Diagnosis Algorithm
ACTH-Dependent (Secondary):
 • Pituitary Dysfunction
 • Hypothalamic Dysfunction
ACTH-Independent (Primary):
Causes of Adrenal ... Insufficiency - ... Differential Diagnosis Algorithm ... ACTH-Dependent ... #Causes #endocrinology
Adrenal Insufficiency Diagnosis Algorithm
Test 1: Baseline AM Cortisol 
 - Beware of major normal value
 -
Adrenal Insufficiency ... Diagnosis Algorithm ... Test 1: Baseline ... 2: ACTH Stimulation ... #endocrinology
Adrenal Insufficiency Algorithm - Cosyntropin Stimulation Test
T-1m: Baseline cortisol drawn
T0: 250 µg cosyntropin given IV
T30m: Repeat
Adrenal Insufficiency ... Algorithm - Cosyntropin ... Stimulation Test ... #Testing #Algorithm ... #Stimulation #endocrinology
Adrenal Insufficiency Diagnosis Algorithm
Clinical features: 
 - Weight loss, anorexia, Weakness, fatigue, GI distress
 - Hypotension,
Diagnosis Algorithm ... skin (due to high ACTH ... cosyntropin stimulation test ... interact with stim test ... Stimulation #StimTest #Endocrinology
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
Primary Adrenal Insufficiency ... aldosterone Causes ... of Adrenal Insufficiency ... : Most Common Causes ... addisons #disease #endocrinology
Adrenal Insufficiency - Diagnosis and Management Summary
Primary Adrenal Insufficiency:
Most Common Cause in the US: Autoimmune Adrenalitis
Other
: Most Common Cause ... Adrenalitis Other causes ... A STIM test can ... ACTH STIM TEST: ... Diagnosis #Management #Endocrinology