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management activation antinxp2 antinxp2dm arteritis cap community dermatology dermatomyositis gca giantcell hematology hemophagocytic hlh lymphohistiocytosis macrophage mas pneumonia pulmonary summary
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Purtilo (XLP) Acquired ... Etoposide/VP16 (100 mg ... #summary #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
the secondary or acquired ... SJIA], systemic lupus ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Rheumatology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... systemic sx + signs ... Treatment of GCA ... per day or 1 mg ... them, but urgent rheumatology
Community Acquired Pneumonia (CAP) - Diagnosis and Management Pneumonia Signs/Symptoms: • Confusion/disorientation (LR + 1.9) • Cough
Community Acquired ... Pneumonia (CAP) - Diagnosis ... Management Pneumonia Signs ... nitrogen level ≥ 20 mg ... aeruginosa Clinical
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
chest (in a V-sign ... auricular papules Clinical ... positive patients Treatment ... Prednisone at 1 mg ... #management #rheumatology
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