13 results
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
Related Disease Clinical ... aorta • Head and neck-limited ... Systemic (head and neck ... Glucocorticoids (0.6 mg ... #rheumatology
Rheumatoid Arthritis Summary
Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders
Signs & Symptoms:
knees, shoulders Signs ... • Ultrasound Diagnosis ... : CLINICAL DIAGNOSIS ... exam and imaging Treatment ... #management #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Etoposide/VP16 (100 mg ... #management #treatment ... #summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... : HLH signs and ... • Bicytopenia Treatment ... #management #treatment ... #hematology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... systemic sx + signs ... Treatment of GCA ... per day or 1 mg ... them, but urgent rheumatology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Physical Exam/Signs ... phenomenon CLL Diagnosis ... microglobulin Treatment ... workup #oncology #hematology
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
double contour sign ... urate level >9 mg ... +Radiographic signs ... level target <6 mg ... #rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... Behcet syndrome (Clinical ... Arthritis, AS Treatment ... #management #signs ... #symptoms #rheumatology
Neurosarcoidosis - Diagnosis and Treatment
 • 5 to 40% of sarcoidosis, Heterogeneous, often inaugural
 • Central
and Treatment ... neurosarcoidosis: Clinical ... Treatment ~ 2 ... Infliximab 3-5 mg ... #neurology #rheumatology
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
weakness in the neck ... auricular papules Clinical ... positive patients Treatment ... Prednisone at 1 mg ... #management #rheumatology