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treatment hematology differential symptoms syndrome workup causes checklist hemophagocytic lymphohistiocytosis sclerosis activation als amyotrophic anesthesia antinxp2 antinxp2dm arteritis arthritis behcet
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Etoposide/VP16 (100 mg ... #management #treatment ... #summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... age, however the disease ... : HLH signs and ... #management #treatment ... #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lymphohistiocytosis (HLH ... Fever is the main clinical ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
neurodegenerative disease ... patients with clinically ... stimulation Clinical ... objective evidence of neurologic ... #management #neurology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
common in Asia • HLA-B51 ... association • M > F Clinical ... skin injury) • Neurologic ... #management #signs ... #symptoms #rheumatology
Chagas Disease - American Trypanosomiasis - Diagnosis and Management Summary Chagas disease (American trypanosomiasis) is an infectious
Trypanosomiasis - Diagnosis ... and Management ... Romana's sign ... Indeterminate form (No signs ... #Management #Treatment
Myasthenic Crisis Checklist - Myasthenia Gravis Evaluation - Chest X-ray and lung ultrasound (exclude other lung
Intubation only if clinically ... Pyridostigmine - New diagnosis ... monitoring (vital signs ... , clinical appearance ... MyastheniaGravis #Checklist #Management
Myasthenia Gravis - Summary • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
50 years in men Diagnosis ... : • Based on clinical ... - Improves clinical ... within 3 years of diagnosis ... #management #neurology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
late adulthood • Diagnosis ... to 8 years Clinical ... than 100 to 300 mg ... and M panel Management ... #diagnosis #management
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
IgG4-Related Disease ... Clinical history ... Glucocorticoids (0.6 mg ... #diagnosis #management ... workup #treatment #rheumatology
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