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diagnosis neurology rheumatology acromegaly als amyotrophic apml barre causes coagulation compartment dic differential differentiation disseminated guillain guillainbarre intravascular lateral leukostasis
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... Lysis of tumor cells ... TLS #diagnosis #management ... #hematology
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Guillain-Barre Pathophysiology ... all extremity, facial ... Sudden death Miller ... associated with Miller ... #diagnosis #management
Bell's Palsy - Diagnosis and Management Summary - GrepMed Handbook Acute Idiopathic Unilateral Facial Nerve (CN7) Palsy Presentation:
Bell's Palsy - Diagnosis ... and Management ... ophthalmoplegia), systemic signs ... within 4m #Bells ... #Treatment #Neurology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Pathophysiology ... APML #diagnosis #management ... #hematology #oncology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
size, coarsening facial ... malignancy Pathophysiology ... Beckwith Wiedemann syndrome ... #Endocrinology ... #Treatment #Pathophysiology
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... of UMN and LMN signs ... diagnosis column Treatment ... gastroenterologists, and social ... neurology #diagnosis #management
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... variants of both • Acral ... + Bleeding Treatment ... diagnosis #causes #treatment ... #management #hematology
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... survival is 93-95% Pathophysiology ... tissue: Epithelioid cells ... iridocyclitis) and facial ... #Signs #Symptoms
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... lacrimal glands: • Focal ... Nephrogenic DI Hematologic ... Adenocarcinoma Treatment ... Diagnosis #Management
Compartment Syndrome Pearls A vicious cycle of increased pressure within a facial compartment leading to compression of
Compartment Syndrome ... pressure within a facial ... Pathophysiology: ... onset of ischemia Treatment ... #diagnosis #management
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