8 results
Electrolyte imbalances are common findings in many diseases. The kidney is a principally responsible organ for
findings in many diseases ... broad range of signs ... and symptoms, from ... and symptoms that ... #electrolyte #algorithm
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
21-OHD in the adrenal ... Signs/Symptoms/Complications ... : • Hyperkalemia ... Labia major & minor ... a scrotum #21HydroxylaseDeficiency
CLINICAL MANIFESTATIONS 
OF ADRENAL INSUFFICIENCY. 

Primary and secondary adrenal insufficiency:
 - Tiredness, weakness, mental depression
Hyperpigmentation - Hyperkalemia ... Autoimmune thyroid disease ... nervous system symptoms ... Insufficiency #Signs ... #Symptoms #Adrenal
Symptoms and Signs of Hypocalcemia
Muscular: Weakness, fatigue, Spasms, cramps
Neurologic: Tetany, Chvostek sign, Trousseau sign, Circumoral and
Symptoms and Signs ... of Hypocalcemia ... paresthesias, Impaired memory ... Hallucinations, dementia ... #Symptoms #Signs
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Alzheimer’s Disease ... chromosome 21) Signs ... episodic and semantic memory ... AlzheimersDisease #Dementia ... #symptoms
Evaluation and Management of Hypokalemia

Hypokalemia is often asymptomatic. Evaluation begins with a search for warning signs
search for warning signs ... or symptoms warranting ... underlying heart disease ... underlying heart disease ... #Evaluation #Algorithm
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features
1) Skin
 • Thin, easily bruisable skin with
Cataracts Labs: Hypokalemia ... the abdomen for adrenal ... tumors • The adrenal ... Hypercortisolism #Diagnosis #signs ... #symptoms #endocrinology
Anorexia Nervosa: Complications
CARDIAC ABNORMALITIES
 - Functional: Low BP, Sinus bradycardia, prolonged QT interval
 - Structural: Reduced
fasting/weight loss RENAL ... Significant Hypotension/ Hypovolemia ... concentrating and memory ... pathophysiology #diagnosis #signs ... #symptoms #psychiatry