27 results
diagnosis management oncology pediatrics clinical dermatology differential disease physicalexam scleroderma syndrome treatment blood corticosteroid injection intraarticular knee leukemia msk orthopedics
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... induced - Bone marrow ... Differential #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Diagnosis of IgA Vasculitis (Henoch-Schönlein Purpura) - French Vasculitis Study Group 1) Suggestive clinical manifestations
especially in the skin ... variant or skin-limited ... arterioles in the skin ... HSP #Diagnosis #Rheumatology ... #Peds #Pediatrics
Behcet's Syndrome - Treatment Ulcers: • Treatment: Topical steroids • Prevention: Colchicine • Azathioprine for refractory disease Arthritis:
refractory disease Skin ... immunosuppressive meds ... immunosuppressive meds ... #pharmacology #rheumatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Hypocellular bone marrow ... Direct Damage to Marrow ... Headaches • Pale skin ... MDS: • ↓ bone marrow ... Anemia #oncology #hematology
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
maculopapular skin ... Leukocytosis (10,000/microL ... Minor criteria include ... Leukocytosis (10,000/microL ... AOSD #diagnosis #rheumatology
Scleroderma Associated Telangiectasia. If you see them-round, often well circumscribed (but can be matte-like too) &
Telangiectasia #clinical #video ... #blanching #skin ... #dermatology #rheumatology
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 SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
bone, joint, and skin ... • Pustular skin ... dermatoses • Skin ... inflammation of the bone marrow ... SAPHO #Syndrome #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Biological + Bone Marrow ... ↑ LDH • Bone marrow ... treatment #summary #rheumatology
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
cold & mottled skin ... Labia major & minor ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... endocrinology #peds
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... lymphocyte > 5000/microL ... AIHA • Bone marrow ... workup #oncology #hematology
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