12 results
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Progression: (+) Immune ... rest LTBI (-) Immune ... Tuberculosis Diagnosis ... Tuberculosis #TB #Diagnosis ... #Management #Treatment
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Progression: (+) Immune ... rest LTBI (-) Immune ... Tuberculosis Diagnosis ... Tuberculosis #TB #Diagnosis ... #Management #Treatment
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
underlying genetic immune ... HLH signs and symptoms ... can mimic common infections ... absent NK cell activity ... #management #treatment
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Immune Reconstitution ... Lymphadenitis, pulmonary ... lymphadenitis, pulmonary ... • Persistently active ... #Management
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
confirm DAH, r/o infection ... or serologies + symptoms ... sparing of the lung ... #differential #diagnosis ... #management #treatment
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
and Management ... increased B-cell activity ... → local immune ... granulomas within the lungs ... Pulmonary: dyspnea
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
- Differential Diagnosis ... hemolytic anemia, PNH, immune ... Legionnaires disease • Pulmonary ... • Toxins • Infection ... associated with any symptoms
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... fibromyalgia) • Infections ... context of primary immune ... Induced Lupus: • Symptoms ... Erythematosus #Diagnosis
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
Amiodarone Induced Lung ... gradually with symptoms ... failure - Infectious ... Improvement in symptoms ... #diagnosis #management
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... Erythema nodosum • Immune ... ingestion • B symptoms ... • PET scan - activity ... hematology #oncology #management