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Antiarrhythmic Medications - Vaughan Williams Classification - Summary Table
Class I agents - Sodium Channel Blockers⠀
Class II
Class I agents ... Blockers⠀ Class ... Blockers Class ... Blockers ⠀ Class ... #pharmacology #
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
Classification: CLASS ... duration: - CLASS ... duration - CLASS ... 1C: Strong Blockade ... Vaughan #Williams #Pharmacology
Antiarrhythmics - Sodium Channel Blockers
Subclasses, Mechanisms, Indications, Side Effects
la - Quinidine, Procainamide
lb - Lidocaine, Mexiletine
Ic -
Antiarrhythmics - Sodium Channel ... - Strong Medicine ... #Blockers #ClassI ... Na #cardiology #pharmacology ... #table #comparison
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Classification: CLASS ... duration - CLASS ... duration - CLASS ... 1C: Strong Blockade ... & AP duration CLASS
Preoperative Risk Evaluation

Major Pre-Op Questions:
1. Does the patient have any modifiable risk factors that could be
b) CHF c) CVA ... ASA class If ... Change in clinical ... • <6mo since stroke ... if result will change