6 results
Diabetes Combination Tablets - Estimated A1c Lowering 
Metformin + DPP4 
• Janumet (metformin + sitagliptin) 
•
Synjardy (metformin + empagliflozin ... Xigduo (metformin + dapagliflozin ... (linagliptin + empagliflozin ... ) • Qtern (dapagliflozin ... #Oral #DM2 #Pharmacology
SGLT2 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits SGLT2 (sodium/glucose cotransporter 2) in the proximal tubule,
gliflozin): • Empagliflozin ... the three • Dapagliflozin ... loss (~2-3kg) • Empagliflozin ... • Euglycemic diabetic ... Pharmacology #Summary #DM2
Selected Clinical Trials of SGLT2 inhibitors in CVD and CKD
EMPA-REG OUTCOME - Empagliflozin lowered CV events
EMPA-REG OUTCOME - Empagliflozin ... DECLARE-TIMI 58 - Dapagliflozin ... EMPEROR-REDUCED - Empagliflozin ... SGLT2 #inhibitors #EBM ... visualabstract #table
SGLT2 inhibitors, also called gliflozins, are a class of medications that alter essential physiology of the
treatment of type II diabetes ... (Invokana®), dapagliflozin ... (Farxiga®) and empagliflozin ... , #dapagliflozin ... , #empagliflozin
Dapagliflozin in Patients with Heart Failure and Reduced Ejection Fraction

CONCLUSIONS:
Among patients with heart failure and a
Dapagliflozin in ... those who received dapagliflozin ... or absence of diabetes ... Kosalan Akilan #Dapagliflozin ... visualabstract #ebm
Summary and links to five landmark trials of intensive control vs standard therapy in DM2:

 UKPDS
standard therapy in DM2 ... pubmed/18539917 #EBM ... #PrimaryCare #Diabetes ... #DM2 #Type2 #Landmark ... Trials #HgbA1c #Targets