8 results
Diabetes Combination Tablets - Estimated A1c Lowering 
Metformin + DPP4 
• Janumet (metformin + sitagliptin) 
•
Synjardy (metformin + empagliflozin ... (linagliptin + empagliflozin ... ) • Qtern (dapagliflozin ... Tablets #Oral #DM2 ... Pharmacology #Pills #Endocrinology
SGLT2 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits SGLT2 (sodium/glucose cotransporter 2) in the proximal tubule,
gliflozin): • Empagliflozin ... the three • Dapagliflozin ... loss (~2-3kg) • Empagliflozin ... • Euglycemic diabetic ... #diabetes #endocrinology
SGLT2 inhibitors, also called gliflozins, are a class of medications that alter essential physiology of the
treatment of type II diabetes ... (Invokana®), dapagliflozin ... (Farxiga®) and empagliflozin ... , #dapagliflozin ... , #empagliflozin
Mechanism of Action for Common Diabetes Medications

 • SGLT2i (Dapagliflozin)
 • TZD (Pioglitazone)
 • Biguanides (Metformin)
Action for Common Diabetes ... • SGLT2i (Dapagliflozin ... sarahthelyon #Diabetes ... pathophysiology #endocrinology
Dapagliflozin in Patients with Heart Failure and Reduced Ejection Fraction

CONCLUSIONS:
Among patients with heart failure and a
Dapagliflozin in ... those who received dapagliflozin ... or absence of diabetes ... Kosalan Akilan #Dapagliflozin ... visualabstract #ebm
Summary and links to five landmark trials of intensive control vs standard therapy in DM2:

 UKPDS
standard therapy in DM2 ... pubmed/18539917 #EBM ... VisualAbstract #Endocrinology ... #PrimaryCare #Diabetes ... #DM2 #Type2 #Landmark
SGLT2 Inhibitors 
SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
class of anti-diabetic ... the first one (Canagliflozin ... #Medications #DM2 ... #Diabetes #Endocrinology
Rybelsus (oral semaglutide) - First Oral GLP-1 Agonist
Dosing:
3 mg daily x 30 days, then 7 mg
compared to SGLT2 empagliflozin ... #semaglutide #Diabetes ... #Pharmacology #Endocrinology