12 results
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... evaluation or workup ... 1,500 cells/µL Workup ... drug reaction, infection ... Differential #diagnosis #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... procedures - Infection ... smear, HIV/HCV testing ... not required in all ... #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
lymphoproliferative disorder ... , autoimmune disorder ... Positive Coombs testing ... malignancies -> CLL ... hemolytic #anemia #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
incompetent • CLL ... weeks without infection ... lymphoproliferative disorders ... Leukemia #diagnosis #workup ... #oncology #hematology
Aortitis - Differential Diagnosis Framework
Non-Infectious Aortitis:
 • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Framework Non-Infectious ... Vasculitides: Giant Cell ... Cancer, Histiocytic disorders ... pneumoniae • Mycobacterial ... Differential #Diagnosis #rheumatology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Consider sickle cell ... inclusions - If infection ... Consider RBC membrane disorder ... Diagnosis #Algorithm #workup ... #hematology #testing
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Mechanical/degenerative disorders ... Morning stiffness lasting ... • Mycobacterial ... - Autoimmune Rheumatologic ... Diagnosis #MSK #rheumatology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
about bacterial infections ... gonorrhea, Lyme, mycobacterial ... Send for cell count ... Joint #Pain #MSK #rheumatology ... #approach #workup
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Screening Tests for All ... metabolic or endocrine disorders ... Arthritis #laboratory #workup ... #Rheumatology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... formed or don’t work ... • Parvovirus infection ... Workup: • Complete ... Syndromes #diagnosis #hematology