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Table of Causes of Acute Liver Injury
#Diagnosis #Hepatology #Acute #Liver #Injury #Causes #Differential #Incidence #Table #Failure
Liver Injury #Diagnosis ... #Hepatology #Acute ... #Liver #Injury ... #Causes #Differential ... Incidence #Table #Failure
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... Liver Failure ( ... Injury (DILI) ... #Hepatology #gastroenterology ... #management #diagnosis
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... - Differential ... Liver Injury: ... #differential # ... diagnosis #algorithm #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Liver Failure ( ... ALT: ↑ • GGT/5-NT ... nucleotidase (5-NT ... chemistry #diagnosis #differential ... #Hepatology #transaminitis
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... liver failure rapidly ... → Multiorgan failure ... infiltration) Differential ... #Pregnancy #hepatology
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
injury (INR > 2 ... > 3 mg/dL) or acute ... liver failure ... #Indications #management ... #hepatology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
subclinical disease to acute ... liver failure ... hepatocellular pattern of liver ... injury, though ... #Hepatology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Acute Hemolytic ... hypoTN, renal failure ... Lung Injury (TRALI ... eruptions, diarrhea, liver ... Transfusion #diagnosis #management
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
- Acute Hemolytic ... hypoTN, renal failure ... Lung Injury (TRALI ... eruptions, diarrhea, liver ... Transfusions #diagnosis #management