12 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... Diagnosis and Workup ... test, ANA (e.g., SLE ... changes), high MCV anemia ... #Workup #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... - Hemolytic anemia ... vasculitis - GPA ... #Diagnosis #hematology ... #rheumatology #
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
- Arthritis Differential ... weeks) Can Be Caused ... Lyme disease) • Mycobacterium ... Diagnosis #MSK # ... rheumatology #Monoarticular
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
belonging to the Mycobacterium ... Cause Many Illnesses ... Hematologic malignancy ... diarrhea, abdominal pain ... Bone Marrow - Anemia
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
- Differential ... Fever/Chills/Joint pain ... bacilli (19%) - Mycobacterium ... arthritis - SLE ... diagnosis #msk #
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Polycythemia - Differential ... an underlying cause ... Better call hematology ... some time, let’s see ... #hematology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Chronic = RA, SLE ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup ... #differential #
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... gastric tumors • Hematology ... Thalassemia, Sickle cell anemia ... #ProteinGap #differential ... #diagnosis #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
infections, bone pain ... activity • ↓ LAP ... -> AML: Blast crises ... - infiltrates (anemia ... #Leukemia #Hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitides - Differential ... tract, and often causes ... , testes -> pain ... vasculitis, and SLE ... #diagnosis #rheumatology