9 results
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
Algorithm for workup ... thrombocytopenic purpura/hemolytic ... thrombocytopenia, Hematology ... #Diagnosis #Differential ... Thrombocytopenia #Evaluation
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Lyme), reactive arthritis ... #rheumatology # ... approach #workup ... #differential # ... diagnosis #arthritis
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
• Inflammatory arthritis ... #Pain #MSK #rheumatology ... #approach #workup ... #differential # ... diagnosis #arthritis
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Approach to Joint ... Differential Diagnosis ... Lyme disease) • Mycobacterium ... Joint #pain #Differential ... Diagnosis #MSK #rheumatology
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Knee Effusions - Differential ... Fever/Chills/Joint ... bacilli (19%) - Mycobacterium ... Effusions: - Hematologic ... Osteochondroma Hematologic
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory Evaluation ... hemorrhage and hemolysis ... WBC count and differential ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Mycobacteria (NTM ... belonging to the Mycobacterium ... Hematologic malignancy ... discomfort, • +/- Hemoptysis ... #Infections #differential
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... vesicular eruption • Joints ... pulmonary infiltrates, hemoptysis ... infiltrates/cavities, hemoptysis ... Palpable purpura, joint
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... first step in evaluation ... (RA, Temporal arteritis ... Gap #ProteinGap #differential ... #diagnosis #hematology