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Here are very large, immature myeloblasts with many nucleoli. A distincitve feature of these blasts is
, immature myeloblasts ... a linear red "Auer ... #Clinical #Path ... #Blood #Smear #Microscopy ... #Auer #Rods #AuerRods
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
): • Microscopic ... +MPO) • Cryoglobulinemic ... Dx: GPA, EGPA, microscopic ... ) pattern: antibodies ... Low levels mixed cryoglobulinemia
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Antibody refers to antibodies ... Using fluorescence microscopy ... likely it will be clinically ... #rheumatology #diagnosis
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Syndrome: • Clinical ... arthralgia, and arthritis ... DDX: • ANCA (Antineutrophil ... vasculitis - GPA, EGPA, microscopic ... SLE), rheumatoid arthritis
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... polarized light microscopy ... double-stranded DNA antibodies ... , which are more ... and RF (if clinical