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How to distinguish a metamyelocyte from a band neutrophil.

- Kyle Bradley, MD
@KyleBradleyMD

#Clinical #Pathology #Microscopy #Blood #Smear
neutrophil ... Clinical #Pathology #Microscopy ... #Blood #Smear # ... Peripheral #Metamyelocytes ... #Bands #Neutrophils
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
neutrophils are ... than segmented neutrophils ... Band neutrophils ... in German) • Neutrophils ... Shift) → Segmented Neutrophil
Evaluation of Leukocytosis:
The term 'leukocyte' applies to any cells within the myeloblast, monoblast, & lymphoid lineages.
Include
granulocytes (neutrophils ... Neutrophil bands ... : Immature neutrophils ... Mature neutrophils ... #NEUTROPHILS #WCC
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
promyelocytes, anemia ... blood smear showed ... hypogranular neutrophils ... , Auer rods in neutrophils ... #Smear #Microscopy
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Algorithm Normal Blood ... Smear • Drugs ... Hypersegmented Neutrophils ... - Low RBC Folate ... Dysplastic • Myelodysplastic
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
bone marrow and peripheral ... leukopenia) Peripheral ... Smear: • Dysplastic ... (hypogranular neutrophils ... blood smear
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
blood smear or ... Leukemia): • Neutrophils ... Leukemia): • Neutrophils ... • Immature/Myeloblasts ... - infiltrates (anemia
Hematology Algorithms 

Anemia is described as a reduction in the proportion of the red blood cells.
proportion of the red blood ... a decrease in all ... three peripheral ... ml (or absolute neutrophil ... neutropenia since neutrophils