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leukemia management approach disease disorders druginduced erythematosus gap globulin hemolysis hemolytic high hodgkins hyperkalemia intravascular joint laboratory lymphocytic lymphoma mds
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Causes Intravascular ... Microangiopathic hemolytic anemia ... #Causes #differential ... #diagnosis #hematology ... #anemia
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... Neutrophils • Immature/Myeloblasts ... - infiltrates (anemia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
lupus cases, drug-dependent ... • Evolution: Chronic ... #sle #comparison ... #table #rheumatology ... #diagnosis #management
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... test, ANA (e.g., SLE ... changes), high MCV anemia ... #Diagnosis #Causes ... #Workup #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... non-Hodgkin lymphoma SLL ... • Neutropenia, anemia ... #workup #oncology ... #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Skin Disease Classification ... lymphopenia, low PLT • Anemia ... : • Chronic B-cell ... #Rheumatology
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
= RA, SLE, psoriatic ... Joint #Pain #MSK #rheumatology ... #approach #workup ... #differential # ... diagnosis #arthritis
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... joint • Systemic lupus ... the presence of anemia ... Screening Tests for Chronic ... #Rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
count (anemia) ... Anemia • Bone ... Megaloblastic Anemia ... Myelophthisic Anemia ... #hematology #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Immune hemolytic anemia ... Hodgkin Lymphoma Workup ... Immunohistochemical studies (to differentiate ... #hematology #oncology
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