8 results
diagnosis algorithm anemia workup causes liver transaminitis abnormal chemistry cholangitis disease disorders elevated extravascular hemolysis hepatitis injury interpretation intravascular liverfunctiontests
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin ... Cold Agglutinins ... 15% of AIHA Primary ... Blood smear - RBC ... #hematology #diagnosis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
usually IgM) (e.g. primary ... cold agglutin disease ... • Intrinsic RBC ... Extravascular #Causes #differential ... #diagnosis #hematology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary ... Cirrhosis (PBC) ... bile ducts Differential ... #Biliary #Cirrhosis ... diagnosis #workup #hepatology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Agglutination - Cold ... agglutinins disease ... hypertension • Unusual RBC ... acanthocytes - Consider RBC ... Algorithm #workup #hematology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Function Tests - Differential ... Ducts - PBC ... - CBD stone, Biliary ... Burak @kwburak #LFTs ... Algorithm #diagnosis #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Autoimmune hepatitis, PBC ... stone, Malignancy, PBC ... hepatitis: < 1 • Cirrhosis ... • LDH: Heart, RBC ... diagnosis #algorithm #hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
decreased PLT count: CBC ... gastric bypass), LFT ... disease), HBsAg/anti-HBc ... unclear, or if a primary ... Causes #Workup #hematology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
hepatitis: < 1 • Cirrhosis ... • Bilirubin: RBC ... cardiac muscle, RBC ... • LDH: Heart, RBC ... #Hepatology #transaminitis
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