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diagnosis algorithm liver transaminitis workup abnormal alkaline anemia chemistry cholangitis disorders elevated elevation extravascular hemolysis hepatitis injury interpretation intravascular liverenzymes
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Function Tests - Differential ... Ducts - PBC ... - CBD stone, Biliary ... Burak @kwburak #LFTs ... Algorithm #diagnosis #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary ... Cirrhosis (PBC) ... intralobular bile ducts causes ... #Biliary #Cirrhosis ... diagnosis #workup #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Algorithm Vascular Causes ... Autoimmune hepatitis, PBC ... stone, Malignancy, PBC ... hepatitis: < 1 • Cirrhosis ... diagnosis #algorithm #hepatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... usually IgM) (e.g. primary ... • Intrinsic RBC ... #differential # ... diagnosis #hematology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Infiltrative • Cirrhosis ... Duct Stone • Biliary ... • Others #LFTs ... #Hepatology #LiverEnzymes ... Diagnosis #Algorithm #Causes
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
) Elevation - Differential ... Intestine - Other causes ... - Drugs - Primary ... (PBC) - Other ... Diagnosis #Algorithm #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
hepatitis: < 1 • Cirrhosis ... • Bilirubin: RBC ... cardiac muscle, RBC ... • LDH: Heart, RBC ... #Hepatology #transaminitis
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
decreased PLT count: CBC ... gastric bypass), LFT ... disease), HBsAg/anti-HBc ... unclear, or if a primary ... #Workup #hematology
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