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diagnosis anemia hemolytic rheumatology agglutinin causes differential hemophagocytic hlh intravascular lymphohistiocytosis oncology sjogrens summary syndrome
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
, lymphoma, idiopathic ... IgM) (e.g. primary ... cold agglutin disease ... • Intrinsic RBC ... differential #diagnosis #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
nodosum • Immune hemolytic ... platelets - WBC ... Lymphoma Treatment ... #hematology #oncology ... #management
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
15% of AIHA Primary ... disorder or lymphoid ... - Monoclonal - Lymphoid ... Blood smear - RBC ... #hematology #diagnosis
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
assessment+++ Primary ... Hemopathies+++: Hodgkin ... , T-cell lymphoma ... , B-cell lymphoma ... solid cancers • Autoimmune
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
biliary cirrhosis ... Nephrogenic DI Hematologic ... lymphoma • B cell ... B cell lymphoma ... #Diagnosis #Management
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