7 results
anemia differential hemolytic agglutinin algorithm cold common cvid hemophagocytic hodgkins hypogammaglobulinemia immunodeficiency immunology injury intravascular liver lymphohistiocytosis oncology sjogrens summary
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... , lymphoma, idiopathic ... usually IgM) (e.g. primary ... #diagnosis #hematology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Algorithm Vascular Causes ... Autoimmune hepatitis ... , HLH • Neoplasm ... lung CA, lymphoma ... #algorithm #hepatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
assessment+++ Primary ... lymphoma, B-cell ... Drugs, Unknown cause ... #management #treatment ... #summary #rheumatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
15% of AIHA Primary ... disorder or lymphoid ... Diagnosis: • hemolytic ... Blood smear - RBC ... #hematology #diagnosis
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
platelets - WBC ... Treatment • Early ... #diagnosis #classification ... #hematology #oncology ... #management
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
hepatitis, primary ... biliary cirrhosis ... • B cell lymphoma ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
and hepatitis ... hemolytic anemia ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
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