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diagnosis anemia differential hemolytic agglutinin algorithm causes classification cold common cvid disease hodgkins hypogammaglobulinemia immunodeficiency immunology injury intravascular oncology rheumatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
) (e.g. lupus, CLL ... , lymphoma, idiopathic ... usually IgM) (e.g. primary ... • Intrinsic RBC ... differential #diagnosis #hematology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Celiac disease • Autoimmune ... : Autoimmune hepatitis ... lung CA, lymphoma ... (hemolysis) • ... diagnosis #algorithm #hepatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
15% of AIHA Primary ... disorder or lymphoid ... - Monoclonal - Lymphoid ... Blood smear - RBC ... #anemia #hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
vasculitis: 10%-16% Liver ... hepatitis, primary ... biliary cirrhosis ... • B cell lymphoma ... #Diagnosis #Management
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to impaired B-cell ... disease • Liver ... diseases and hepatitis ... hemolytic anemia ... hypogammaglobulinemia #immunology #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
nodosum • Immune hemolytic ... platelets - WBC ... Treatment • Early ... classification #hematology ... #oncology #management
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