10 results
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Pruritus - Generalized ... and Primary Causes ... Creatinine & BUN: • Chronic ... Hyperthyroidism CBC ... Myelodisplastic syndrome
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
blasts and high WBC ... count cause hyperviscosity ... • Lab values: WBC ... • Treatment: ... diagnosis #management #hematology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm

Blood Glucose:
 • Diabetes Mellitus
Liver Function Tests/Enzymes:
Creatinine & BUN: • Chronic ... Hyperthyroidism CBC ... Myelodisplastic syndrome ... #secondary #systemic ... Diagnosis #Algorithm #causes
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... sweats, bleeding • Pruritis ... Neutrophils • Immature/Myeloblasts ... • Tumor lysis syndrome ... #Leukemia #Hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... rendering the immune system ... Lymphocytosis on CBC ... microglobulin Treatment ... workup #oncology #hematology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
thiazidic, PPI, ACE, calcium-b ... Discontinuation of causal ... months to years) Systemic ... • Evolution: Chronic ... comparison #table #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Eosinophilia, asthma, chronic ... tract, and often causes ... • Cogan Syndrome ... Lab Tests: • CBC ... differential #diagnosis #rheumatology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
maculopapular rash, pruritis ... Causes purpura & ... binds to serum calcium ... include: Malaria, Borrellia ... diagnosis #management #hematology
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Synovial Fluid: • WBCs ... Acute Pseudogout: Treatment ... polyarticular CPPD • Systemic ... Crowned Dens Syndrome ... Deposition #Disease #Rheumatology
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... • Conduction system ... statins - probably caused ... muscular atrophy • Chronic ... Myositis #Myopathy #rheumatology