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blood management anemia differential extravascular hemolytic mds myelodysplastic oncology syndromes transfusion
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... thrombocytopenic purpura (TTP ... usually IgG) (e.g. lupus ... G6PD deficiency) ... #diagnosis #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... Crossmatch - involves testing ... recipients w/ IgA deficiency ... diagnosis #management ... #hematology #reactions
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Transfusion Reaction ... recipients w/ IgA deficiency ... false negatives on testing ... #Transfusion #diagnosis ... #management #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... • Hairy Cell Leukemia ... Workup: • Complete ... #Syndromes #diagnosis ... #hematology #oncology
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