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diagnosis oncology algorithm anemia aplastic dermatology effusions gap globulin knee lymphadenopathy management mds miami mnemonic msk myelodysplastic petechial protein proteingap
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Chronic inflammatory disorders ... vera (PV) • Myelodysplastic ... syndrome • Myelofibrosis ... Chronic myeloid leukemia ... #hematology #secondary
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Rash - Differential ... Vasculitis - Collagen disorders ... cryoglobulins • Skin ... #dermatology #physicalexam
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders ... just beneath the skin ... by bleeding (petechiae ... blood count with differential ... #hematology #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Neutrophils • Immature/Myeloblasts ... Significant ↓ PLT: Petechiae ... • Tumor lysis syndrome ... CLL -> Invade Skin ... #Hematology #Oncology
MIAMI Mnemonic for Differential Diagnosis of Lymphadenopathy Malignancies - Kaposi sarcoma, leukemias, lymphomas, metastases, skin neoplasms Infections -
Kaposi sarcoma, leukemias ... lymphomas, metastases, skin ... cytomegalovirus, hepatitis, herpes ... arthritis, Sjögren syndrome ... sarcoidosis Iatrogenic causes
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 Causes of Knee Effusions - Differential Diagnosis Framework Knee Effusion Red Flags: 1. Fever/Chills/Joint pain/Night sweats/Weight loss - DDX: -
Causes of Knee Effusions ... - Differential ... Chikungunya - Herpes ... - Leukemia ... diagnosis #msk #physicalexam
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Headaches • Pale skin ... bleeding, and petechiae ... Causes: • Constitutional ... virus (EBV) • Leukemia ... Anemia #oncology #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
gammopathy, and skin ... changes (POEMS syndrome ... Connective tissue disorders ... : Lymphoma, Leukemia ... Gap #ProteinGap #differential
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